The National Research Institute for Veterinary Virology and Microbiology of Russia was established according to Order 300 of the USSR Minister of Agriculture of November 13, 1958.

The Institute has been granted licenses for the manufacture and marketing of veterinary preparations and for laboratory and diagnostic activities and is authorized for conducting educational activity in post-graduate professional training. Post-graduate courses have been organized and are functioning, and a Dissertational Board has been established in the Institute. 

Original and effective diagnostic preparations for laboratory diagnostics and differentiation of African swine fever and classical swine fever, for laboratory diagnostics of rinderpest, peste des petits ruminants, bluetongue, sheep & goat pox, caprine arthritis-encephalitis, avian influenza, Newcastle disease, rabies, epizootic hemorrhagic disease of deer, anthrax, and also some exotic viral infections like Nairobi disease, Akabane disease, Ibaraki disease, Border disease, and many others have been constructed. 

Using the research achievements of the Institute in 80-s, an unexpectedly emerged epizootic of rabbit hemorrhagic disease was quickly eradicated, and anthrax morbidity rates among animals was minimized. In 90-s Rinderpest spread in the Tuva Republic and the Chita region of Russia, and bluetongue spread in the Buryat Republic were prevented. The Institute researchers developed a dust vaccine against classical swine fever which has no analogues in the world and is in great demand among veterinary practitioners. Application of new rabies vaccines for oral application in hunting reserves promotes improvement of the epizootic situation for rabies.  

The Institute has rendered great assistance in eradication of African swine fever in Cuba and of Rinderpest in Mongolia.